Ma Xiaoming, Kikuta Hideaki, Ishiguro Nobuhisa, Yoshioka Mikio, Ebihara Takashi, Murai Teiko, Kobayashi Intetu, Kobayashi Kunihiko
Department of Pediatrics, Hokkaido University School of Medicine, N-15 W-7, Kita-ku, Sapporo 060-8638, Japan.
J Clin Microbiol. 2002 Oct;40(10):3835-7. doi: 10.1128/JCM.40.10.3835-3837.2002.
A total of 66 clinical isolates of group A streptococci (GAS) were obtained from 66 Japanese children with pharyngitis. The prtF1 gene (encoding fibronectin-binding protein F1) and the sic gene (encoding the streptococcal inhibitor of complement) were present in 51 (77.3%) and 48 (72.7%) of the 66 isolates, respectively. These results indicated that a high prevalence of two virulence genes, prtF1 and sic, is characteristic of GAS in Japan.
从66名患咽炎的日本儿童中总共获得了66株A组链球菌(GAS)临床分离株。prtF1基因(编码纤连蛋白结合蛋白F1)和sic基因(编码补体链球菌抑制剂)分别存在于66株分离株中的51株(77.3%)和48株(72.7%)中。这些结果表明,prtF1和sic这两种毒力基因在日本GAS中具有很高的流行率。