Mounier-Vehier C, Amah G, Covillard J, Jaboureck O, Phan T M
Service de médecine interne et HTA, hôpital cardiologique, CHRU, 59037 Lille.
Arch Mal Coeur Vaiss. 2002 Jul-Aug;95(7-8):667-72.
To define the prevalence of cardiovascular risk (CVR) levels in a population of hypertensive patients (whether treated or not) monitored by General Practitioners, using the stratification system proposed by the ANAES in 2000.
Between January and July 2001, a nation-wide survey was carried out based on a representative sample of 8,177 General Practitioners spread evenly throughout all of the 22 administrative regions in France. The evaluation of CVR levels took into account blood pressure readings as well as CVR factors and indicators.
This survey covered 16,358 patients (53.2% men, 46% women; mean age = 62.5 +/- 11.9 years; BMI = 27.3 +/- 4.5 kg/m2) with a mean history of hypertension of 7 +/- 7 years. The most common CVR factors were dyslipidemia (59.5%), smoking (19%) and diabetes (16%). Concomitant target organ damage was recorded in 17% and heart disease in 21.8%. One patient in four had more than three CVR factors; respectively 56.5%, 30.9% and 12.5% of the patients had mild, moderate or severe hypertension. More than 50% of the patients were classified as being at "high" or "very high" CV risk. The distribution of risk levels was similar throughout the country with a North-South gradient of the high/very high levels. Only 17% of the patients being treated had completely normal blood pressure (< 140/190 mmHg), although 19% more count as normal if the limit values are included.
The main objective of this large-scale, nation-wide epidemiological survey was to evaluate how well CVR is being managed in a representative sample of patients with high blood pressure. In general, none of the risk factors is adequately controlled, especially in populations considered as being at high CVR. Moreover, the notion of CVR has only been partially assimilated by General Practitioners.
采用2000年ANAES提出的分层系统,确定由全科医生监测的高血压患者群体(无论是否接受治疗)中心血管风险(CVR)水平的患病率。
2001年1月至7月间,基于法国22个行政区均匀分布的8177名全科医生的代表性样本开展了一项全国性调查。CVR水平的评估考虑了血压读数以及CVR因素和指标。
本次调查涵盖了16358名患者(男性占53.2%,女性占46%;平均年龄=62.5±11.9岁;体重指数=27.3±4.5kg/m²),平均高血压病史为7±7年。最常见的CVR因素为血脂异常(59.5%)、吸烟(19%)和糖尿病(16%)。伴有靶器官损害的记录为17%,心脏病为21.8%。四分之一的患者有超过三种CVR因素;分别有56.5%、30.9%和12.5%的患者患有轻度、中度或重度高血压。超过50%的患者被归类为具有“高”或“极高”心血管风险。风险水平的分布在全国范围内相似,高/极高水平存在南北梯度差异。尽管将限值纳入计算后另有19%的患者血压算作正常,但接受治疗的患者中只有17%的血压完全正常(<140/90mmHg)。
这项大规模全国性流行病学调查的主要目的是评估在高血压患者代表性样本中CVR的管理情况。总体而言,没有一个风险因素得到充分控制,尤其是在被认为具有高CVR的人群中。此外,全科医生对CVR概念的理解仅处于部分吸收阶段。