Usall J, Haro J M, Ochoa S, Márquez M, Araya S
Sant Joan de Déu, Serveis Salut Mental, Barcelona, Catalonia, Spain.
Acta Psychiatr Scand. 2002 Nov;106(5):337-42. doi: 10.1034/j.1600-0447.2002.01351.x.
To study the relevance of gender on social functioning in schizophrenia.
A sample of 200 schizophrenic (DSM-IV criteria) out-patients were followed-up during 2 years and were administered the following instruments: Positive and Negative Symptom Scale (PANSS), Disability Assessment Scale (DAS-sv), and Global Assessment of Functioning (GAF) Scale. A regression model was created with DAS and GAF as dependent variables, and gender, PANSS, age of onset, duration of illness and marital status as independent variables. Separate regression models were then generated for females and males.
Gender influenced significantly on DAS and GAF, with men showing worse functioning. In gender specific analyses, we found a significant influence of illness duration and Positive and Negative PANSS on social functioning in men, and of age at onset and Negative PANSS in women.
Gender had a significant influence on social functioning in schizophrenia, even after adjusting for the other independent variables.
研究性别与精神分裂症社会功能的相关性。
对200名符合精神疾病诊断与统计手册第四版（DSM-IV）标准的精神分裂症门诊患者进行了为期2年的随访，并使用了以下工具：阳性与阴性症状量表（PANSS）、残疾评定量表（DAS-sv）和功能总体评定量表（GAF）。以DAS和GAF作为因变量，以性别、PANSS、起病年龄、病程和婚姻状况作为自变量建立回归模型。然后分别为女性和男性建立回归模型。
性别对DAS和GAF有显著影响，男性的功能表现更差。在性别特异性分析中，我们发现病程以及阳性与阴性PANSS对男性的社会功能有显著影响，而起病年龄和阴性PANSS对女性有显著影响。
即使在调整了其他自变量之后，性别对精神分裂症的社会功能仍有显著影响。
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