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住院医师日间过度嗜睡的风险及影响

The risks and implications of excessive daytime sleepiness in resident physicians.

作者信息

Howard Steven K, Gaba David M, Rosekind Mark R, Zarcone Vincent P

机构信息

Patient Safety Center of Inquiry, VA Palo Alto Health Care System, and the Department of Anesthesia, Stanford University School of Medicine, Stanford, California, USA.

出版信息

Acad Med. 2002 Oct;77(10):1019-25. doi: 10.1097/00001888-200210000-00015.

Abstract

PURPOSE

To assess the levels of physiologic and subjective sleepiness in residents in three conditions: (1) during a normal (baseline) work schedule, (2) after an in-hospital 24-hour on-call period, and (3) following a period of extended sleep.

METHOD

In 1996, a within-subjects, repeated-measures study was performed with a volunteer sample of 11 anesthesia residents from the Stanford University School of Medicine using three separate experimental conditions. Sixteen residents were recruited and 11 of the 16 completed the three separate experimental conditions. Daytime sleepiness was assessed using the Multiple Sleep Latency Test (MSLT).

RESULTS

MSLT scores were shorter in the baseline (6.7 min) and post-call (4.9 min) conditions, compared with the extended-sleep condition (12 min, p =.0001) and there was no significant difference between the baseline and post-call conditions (p =.07). There was a significant main effect for both condition (p =.0001) and time of day (p =.0003). Subjects were inaccurate in subjectively identifying sleep onset compared with EEG measures (incorrect on 49% of EEG-determined sleep episodes).

CONCLUSION

Residents' daytime sleepiness in both baseline and post-call conditions was near or below levels associated with clinical sleep disorders. Extending sleep time resulted in normal levels of daytime sleepiness. The residents were subjectively inaccurate determining EEG-defined sleep onset. Based on the findings from this and other studies, reforms of residents' work and duty hours are justified.

摘要

目的

评估住院医师在三种情况下的生理和主观困倦程度:(1)正常(基线)工作时间表期间;(2)住院24小时值班期后;(3)延长睡眠时间后。

方法

1996年,对斯坦福大学医学院11名麻醉科住院医师志愿者样本进行了一项受试者内重复测量研究,采用三种不同的实验条件。招募了16名住院医师,其中11名完成了三种不同的实验条件。使用多次睡眠潜伏期测试(MSLT)评估白天嗜睡情况。

结果

与延长睡眠条件(12分钟,p = 0.0001)相比,基线(6.7分钟)和值班后(4.9分钟)条件下的MSLT分数较短,基线和值班后条件之间无显著差异(p = 0.07)。条件(p = 0.0001)和一天中的时间(p = 0.0003)均有显著的主效应。与脑电图测量相比,受试者在主观确定睡眠开始时间方面不准确(在脑电图确定的睡眠发作中49%不正确)。

结论

住院医师在基线和值班后条件下的白天嗜睡程度接近或低于与临床睡眠障碍相关的水平。延长睡眠时间可导致白天嗜睡程度正常。住院医师在主观确定脑电图定义的睡眠开始时间方面不准确。基于本研究和其他研究的结果,对住院医师工作和值班时间进行改革是合理的。

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