急性冷暴露对用6-羟基多巴胺处理的大鼠血液成分的影响（作者译）
[Effect of acute cold exposure on blood composition in rats treated with 6-Hydroxydopamine (author's transl)].
作者信息
Honma K, Fukushima N, Maekubo H, Itoh S
出版信息
Hokkaido Igaku Zasshi. 1975 May;50(3):299-303.
Rats injected with 6-hydroxydopamine (6-OHDA) into the lateral ventricle showed greater elevation in plasma FFA and beta-hydroxybutyrate and significant decrease in blood sugar and lactate following acute cold exposure at -10 degrees C for 2 hours. Changes in the blood composition induced by the cold exposure in rats treated with 6-OHDA intravenously were not different from those observed in control rats. Adrenomedullectomized rats treated with 6-OHDA responded to the cold exposure with rather marked elevation in plasma FFA and beta-hydroxybutyrate. These results were discussed from the view-point of compensatory changes in metabolic regulation in the absence of norepinephrine.
向侧脑室内注射6-羟基多巴胺（6-OHDA）的大鼠，在-10℃急性冷暴露2小时后，血浆游离脂肪酸（FFA）和β-羟基丁酸水平升高幅度更大，血糖和乳酸水平显著降低。静脉注射6-OHDA的大鼠经冷暴露后血液成分的变化与对照大鼠观察到的变化无差异。用6-OHDA处理的肾上腺髓质切除大鼠对冷暴露的反应是血浆FFA和β-羟基丁酸显著升高。从去甲肾上腺素缺乏时代谢调节的代偿性变化角度对这些结果进行了讨论。
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