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A copper connection to the uptake of platinum anticancer drugs.

作者信息

Nitiss John L

机构信息

Molecular Pharmacology Department, St. Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN 38105, USA.

出版信息

Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):13963-5. doi: 10.1073/pnas.232574299. Epub 2002 Oct 21.

Abstract
摘要

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本文引用的文献

1
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals.
Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14298-302. doi: 10.1073/pnas.162491399. Epub 2002 Oct 7.
2
Functional profiling of the Saccharomyces cerevisiae genome.
Nature. 2002 Jul 25;418(6896):387-91. doi: 10.1038/nature00935.
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Copper ion-sensing transcription factor Mac1p post-translationally controls the degradation of its target gene product Ctr1p.
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A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity.
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Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development.
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The copper transporter CTR1 provides an essential function in mammalian embryonic development.
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The TOR kinases link nutrient sensing to cell growth.
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