Sheen Christopher L, Dillon John F, Bateman D Nicholas, Simpson Kenneth J, MacDonald Thomas M
Medicines Monitoring Unit, Department of Gastroenterology, Ninewells Hospital, Dundee, DD1 9SY.
Br J Clin Pharmacol. 2002 Oct;54(4):430-2. doi: 10.1046/j.1365-2125.2002.t01-1-01671.x.
To investigate the death rate due to paracetamol poisoning in Scotland and what effect the reduction in over-the-counter paracetamol pack sizes in 1998 had on the death rate.
Records from 1994 to 2000 were examined to identify the number and annual incidence of paracetamol-related deaths. Numbers of deaths before and after the pack size reduction were compared.
No significant differences were shown due to the pack size reduction. The Scottish paracetamol-related death rate was twice as high as in England and Wales.
Further measures to reduce paracetamol-related morbidity and mortality in Scotland should be considered.
调查苏格兰对乙酰氨基酚中毒导致的死亡率,以及1998年非处方对乙酰氨基酚包装规格减小对死亡率有何影响。
检查1994年至2000年的记录,以确定对乙酰氨基酚相关死亡的数量和年发病率。比较包装规格减小前后的死亡人数。
未显示出因包装规格减小而有显著差异。苏格兰对乙酰氨基酚相关死亡率是英格兰和威尔士的两倍。
应考虑采取进一步措施降低苏格兰对乙酰氨基酚相关的发病率和死亡率。