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[肾癌胰腺转移灶的外科治疗]

[Surgical treatment of pancreatic metastases from renal carcinoma].

作者信息

Peschaud F, Cheynel N, Hagry O, Tremeaux J C, Rat P, Favre J P

机构信息

Service de chirurgie digestive, thoracique et cancérologique, Hôpital du Bocage, 2, Boulevard Maréchal-de-Lattre-de-Tassigny, BP 1542, 21034 Dijon, France.

出版信息

Ann Chir. 2002 Sep;127(7):527-31. doi: 10.1016/s0003-3944(02)00839-8.

Abstract

OBJECTIVES

Pancreatic metastases from renal carcinoma are poorly known. The aim of this study was to report clinical and radiological manifestations, the treatment performed, and the observed survival in 7 patients with this rare entity.

RESULTS

All patients were operated on. One patient had nonresectable tumor. Six patients underwent curative resection. There was one postoperative death. Follow-up after pancreatectomy ranged from 6 months to 3 years. Two patients developed extra-pancreatic metastases one year and 3 years after pancreatectomy respectively.

CONCLUSIONS

Pancreatic metastases from renal carcinoma are rare and often occur several years after nephrectomy. However their resection is often possible and allows a good long-term survival.

PATIENTS AND METHODS

From 1988 to 2000, 7 patients (5 men and 2 women, mean age = 66 years) with pancreatic metastases from a renal cell carcinoma were observed in the same center. One patient had synchronous metastasis; in the 6 others, metastases were diagnosed 4 to 16 years after nephrectomy, and were revealed by pain (n = 2), gastrointestinal bleeding (n = 1), faintness (n = 1) or routine follow-up (n = 2). The diagnosis of metastases was made by contrast-enhanced abdominal CT-scan.

摘要

目的

肾癌胰腺转移瘤鲜为人知。本研究旨在报告7例患有这种罕见疾病的患者的临床和影像学表现、所采取的治疗方法以及观察到的生存情况。

结果

所有患者均接受了手术。1例患者肿瘤无法切除。6例患者接受了根治性切除。有1例术后死亡。胰腺切除术后的随访时间为6个月至3年。2例患者分别在胰腺切除术后1年和3年出现胰腺外转移。

结论

肾癌胰腺转移瘤罕见,且常发生在肾切除术后数年。然而,其切除通常是可行的,并能带来良好的长期生存。

患者与方法

1988年至2000年,在同一中心观察到7例(5例男性和2例女性,平均年龄 = 66岁)患有肾细胞癌胰腺转移瘤的患者。1例患者为同时性转移;其他6例患者在肾切除术后4至16年被诊断为转移,症状表现为疼痛(2例)、胃肠道出血(1例)、晕厥(1例)或常规随访(2例)。通过增强腹部CT扫描做出转移瘤的诊断。

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