Prosseda Gianni, Falconi Maurizio, Nicoletti Mauro, Casalino Mariassunta, Micheli Gioacchino, Colonna Bianca
Dip Biologia Cellulare e dello Sviluppo, Università La Sapienza, Rome, Italy.
Res Microbiol. 2002 Sep;153(7):461-8. doi: 10.1016/s0923-2508(02)01346-3.
The contribution of histone-like proteins to the transcriptional regulation of virulence gene networks is a common feature among pathogenic bacteria. In this article we review current knowledge about the regulative role of major histone-like proteins in the silencing/activation of the invasivity phenotype of Shigella, the etiological agent of bacillary dissentery.
类组蛋白对毒力基因网络转录调控的作用是病原菌的一个共同特征。在本文中,我们综述了关于主要类组蛋白在志贺氏菌(细菌性痢疾的病原体)侵袭性表型沉默/激活中的调控作用的现有知识。