Gallagher A M, Savage J M, Murray L J, Davey Smith G, Young I S, Robson P J, Neville C E, Cran G, Strain J J, Boreham C A
Northern Ireland Centre for Diet and Health (NICHE), School of Biomedical Sciences, University of Ulster, Cromore Road, Coleraine BT52 1SA, UK.
Public Health. 2002 Nov;116(6):332-40. doi: 10.1038/sj.ph.1900871.
The Young Hearts (YH) Project is an ongoing study of biological and behavioural risk factors for cardiovascular disease in a representative sample of young people from Northern Ireland, a region of high coronary mortality. This article describes the cross-sectional clinical, dietary and lifestyle data obtained from individuals (aged 20-25 y) who participated in phase 3 of the project (YH3). A total of 489 individuals (251 males, 238 females) participated in YH3 (48.2% response rate). Some 31.1% of participants at YH3 were overweight (BMI >25 kg/m(2)) with 4.4% of males and 8.0% of females were obese (BMI >30 kg/m(2)). More females than males had a very poor fitness (55.0 vs 22.1%, chi-squared 51.70, d.f. 1, P<0.001) and did not participate in any sporting or exercise activity (38.4 vs 24.9%, chi-squared 10.26, d.f. 1, P=0.001). Over 20% of participants had a raised total serum cholesterol (>5.2 mmol/l). More females had a raised serum LDL-cholesterol (>3.0 mmol/l) than males (44.6 vs 34.6%, chi-squared 4.39, d.f. 1, P<0.05). Over 46% of participants reported energy intakes from fat above recommended levels, and 68.5% of participants had saturated fat intakes above those recommended (Dietary reference values for food energy and nutrients for the United Kingdom. HMSO: London, 1991). Just over half of the study population reported alcohol intakes in excess of recommended sensible limits set by the Royal College of Physicians (A great and growing evil: the medical consequences of alcohol abuse. Tavistock: London, 1987), with 36.7% of males and 13.4% of females reporting intakes over twice these recommended limits. A total of 37% of the study population smoked. During young adulthood, individuals may be less amenable to attend a health-related study and recruitment of participants to the current phase of the study proved a major problem. However, these data constitute a unique developmental record from adolescence to young adulthood in a cohort from Northern Ireland and provide additional information on the impact of early life, childhood and young adulthood on the development of risk for chronic disease.
“年轻心脏”(YH)项目是一项正在进行的研究,旨在调查北爱尔兰具有代表性的年轻人群体中,心血管疾病的生物和行为风险因素。北爱尔兰是冠心病死亡率较高的地区。本文描述了从参与该项目第三阶段(YH3)的个体(年龄在20 - 25岁之间)中获取的横断面临床、饮食和生活方式数据。共有489人(251名男性,238名女性)参与了YH3(应答率为48.2%)。YH3中约31.1%的参与者超重(BMI>25 kg/m²),其中4.4%的男性和8.0%的女性肥胖(BMI>30 kg/m²)。身体状况极差的女性多于男性(55.0%对22.1%,卡方值51.70,自由度1,P<0.001),且不参加任何体育或锻炼活动的女性也多于男性(38.4%对24.9%,卡方值10.26,自由度1,P = 0.001)。超过20%的参与者总血清胆固醇升高(>5.2 mmol/l)。血清低密度脂蛋白胆固醇升高(>3.0 mmol/l)的女性多于男性(44.6%对34.6%,卡方值4.39,自由度1,P<0.05)。超过46%的参与者报告脂肪能量摄入高于推荐水平,68.5%的参与者饱和脂肪摄入量高于推荐水平(《英国食物能量和营养素膳食参考值》。英国皇家文书局:伦敦,1991年)。略超过一半的研究人群报告酒精摄入量超过了皇家内科医师学院设定的推荐合理限量(《一种巨大且日益严重的危害:酒精滥用的医学后果》。塔维斯托克出版社:伦敦,1987年),36.7%的男性和13.4%的女性报告摄入量超过这些推荐限量的两倍。共有37%的研究人群吸烟。在成年早期,个体可能不太愿意参加与健康相关的研究,而招募参与者进入研究的当前阶段被证明是一个主要问题。然而,这些数据构成了北爱尔兰一个队列从青春期到成年早期独特的发育记录,并提供了关于生命早期、童年和成年早期对慢性病风险发展影响的额外信息。