Prochukhanov R A
Arkh Patol. 1975;37(2):77-91.
The article is of a surveying character and is dedicated to objectives of quantititative histo mammary gland). Problems connected with standardization of preparation of the material and carrying out of histochemical reactions, a complex of histochemical criteria and principles of their selection, are considered. A variant of mathematical treatment of material by a computer, including analysis of distribution and correlation characteristic, is suggested. The complex functional-morphological method (marker) suggested, with its quantitative assessment, is, in the opinion of the author, a qualitatively new basis for mathematical descriptions of organs and systems and their modelling and opens up new perspectives both in physiology and pathology.
本文具有综述性质,致力于乳腺定量组织学的目标。文中探讨了与材料制备标准化以及组织化学反应实施相关的问题,还考虑了一系列组织化学标准及其选择原则。提出了一种利用计算机对材料进行数学处理的方法,包括分析分布和相关性特征。作者认为,所提出的综合功能形态学方法(标记物)及其定量评估,是对器官和系统进行数学描述及其建模的全新定性基础,为生理学和病理学研究开辟了新的前景。