Simbirtsev A S, Konusova V G, Mchelidze G Sh, Fidarov E Z, Paramonov B A, Chebotarev V Yu
State Institute of Extra Pure Biopreparations, St. Petersburg.
Bull Exp Biol Med. 2002 May;133(5):457-60. doi: 10.1023/a:1019805603373.
The effects of Biopin (ointment containing pine resin) used in the treatment of burns, wounds, and pyoinflammatory processes on cell composition of the wound surface (smears) and granulation tissue were studied on rats. In vitro antibacterial activity of the drug was also evaluated. At the early stage of inflammation Biopin modulated the nonspecific and inhibited specific cell immune response, normalized hemodynamics in the inflammation focus, activated synthetic processes in the wound, and was effective towards anaerobes and bacilli.
研究了用于治疗烧伤、伤口和脓性炎症过程的碧奥平(含松脂软膏)对大鼠伤口表面(涂片)和肉芽组织细胞组成的影响。还评估了该药物的体外抗菌活性。在炎症早期,碧奥平调节非特异性免疫反应并抑制特异性细胞免疫反应,使炎症灶的血流动力学恢复正常,激活伤口的合成过程,对厌氧菌和杆菌有效。