Gaughen John R, Jensen Mary E, Schweickert Patricia A, Marx William F, Kallmes David F
Department of Radiology, University of Virginia Health Services, Charlottesville, VA, USA.
AJNR Am J Neuroradiol. 2002 Nov-Dec;23(10):1657-61.
Recurrent pain after vertebroplasty is relatively common, usually representing a new fracture at a different vertebral level. In a small cohort described herein, clinical and imaging findings indicated that recurrent pain arose from abnormality of the previously treated level. Our purpose was to demonstrate that repeat percutaneous vertebroplasty performed within the same fractured vertebra can offer therapeutic benefit for patients with recurrent pain after initial treatment.
We conducted a retrospective review of consecutive vertebroplasty procedures performed at our institution to define a patient population that underwent repeat vertebroplasty for recurrent pain at previously treated vertebral levels. We identified six such patients over an 8-year period, and clinical outcomes were assessed through quantitative measurements of pre- and postoperative levels of pain and mobility.
Initial vertebroplasty resulted in substantial improvement in pain in all six patients. Patients developed recurrent pain between 8 days and 167 days after initial vertebroplasty. After repeat vertebroplasty, five of the six patients reported a reduction of at least 3 points in their rating of pain, with a mean reduction of 6.5 points and a mean postoperative pain level of 3.5 points (11-point scale). Four of six patients reported impaired mobility before repeat vertebroplasty, and all four demonstrated a postoperative improvement in mobility. Mean increase in mobility was 1.50 points, and the mean postoperative mobility impairment was 0.25 points (5-point scale).
The clinical outcomes of the patients within this case series suggest that repeat percutaneous vertebroplasty performed at previously treated vertebral levels for recurrent pain offer therapeutic benefit.
椎体成形术后复发性疼痛相对常见,通常表现为不同椎体水平出现新的骨折。在本文所述的一个小队列中,临床和影像学检查结果表明,复发性疼痛源于先前治疗椎体水平的异常。我们的目的是证明在同一骨折椎体内行重复经皮椎体成形术可为初始治疗后出现复发性疼痛的患者带来治疗益处。
我们对在本机构连续进行的椎体成形术进行了回顾性分析,以确定在先前治疗的椎体水平因复发性疼痛而接受重复椎体成形术的患者群体。我们在8年期间确定了6例此类患者,并通过对术前和术后疼痛及活动度水平进行定量测量来评估临床结局。
初始椎体成形术使所有6例患者的疼痛均有显著改善。患者在初始椎体成形术后8天至167天之间出现复发性疼痛。重复椎体成形术后,6例患者中有5例报告疼痛评分至少降低了3分,平均降低6.5分,术后平均疼痛水平为3.5分(11分制)。6例患者中有4例在重复椎体成形术前报告活动度受损,所有4例患者术后活动度均有改善。活动度平均增加1.50分,术后平均活动度受损为0.25分(5分制)。
该病例系列中患者的临床结局表明,在先前治疗的椎体水平因复发性疼痛而行重复经皮椎体成形术具有治疗益处。