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[巴利亚多利德省各地区的大环内酯类药物消费量]

[Macrolide consumption according to geographic areas in the province of Valladolid].

作者信息

Pastor Enrique, Eiros José María, Mayo Agustín

机构信息

Médico de Familia. Centro de Salud Rondilla I. Valladolid. Spain.

出版信息

Enferm Infecc Microbiol Clin. 2002 Dec;20(10):498-502. doi: 10.1016/s0213-005x(02)72852-8.

Abstract

AIM

In our setting systemic antibiotics comprise one of the most extensively used treatment groups in Primary Care. Among these, the use of macrolides has increased considerably in recent years and has shown variations in consumption according to geographic areas. This work was performed to quantify these variations.

METHODS

Information on macrolide consumption in six geographic areas of the providence of Valladolid over 5 years (1996-2000) was compiled through data provided by International Marketing Services. The indicator used was the defined daily dose per 1,000 inhabitants and day.

RESULTS

Macrolide consumption varied considerably among the areas studied. Greatest use of the major macrolides (clarithromycin, erythromycin and spiramycin) was observed in the area of Medina del Campo. Use of the remaining active principles in this subgroup of antibiotics showed the following distribution: midecamycin in the city of Valladolid, azithromycin in Area Norte and roxithromycin in Area Sur.

CONCLUSIONS

Macrolide consumption showed significant differences according to areas, with some areas showing double the consumption of others. This diversity indicates specific patterns of use of the antimicrobials in this subgroup.

摘要

目的

在我们的医疗环境中,全身性抗生素是基层医疗中使用最为广泛的治疗药物类别之一。其中,近年来大环内酯类药物的使用量大幅增加,且在不同地理区域的消费量存在差异。开展这项研究旨在量化这些差异。

方法

通过国际营销服务公司提供的数据,收集了巴利亚多利德省六个地理区域在5年期间(1996 - 2000年)的大环内酯类药物消费信息。所使用的指标是每1000居民每日的限定日剂量。

结果

在所研究的区域中,大环内酯类药物的消费量差异显著。在梅迪纳德尔坎波地区观察到主要大环内酯类药物(克拉霉素、红霉素和螺旋霉素)的使用量最大。在该类抗生素的这一亚组中,其余活性成分的使用情况如下:米卡霉素在巴利亚多利德市使用,阿奇霉素在北区使用,罗红霉素在南区使用。

结论

大环内酯类药物的消费量因地区而异,一些地区的消费量是其他地区的两倍。这种差异表明了该亚组抗菌药物的特定使用模式。

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