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用氰基丙烯酸正丁酯进行内镜治疗胆漏

Endoscopic treatment of biliary leakage with n-butyl-2 cyanoacrylate.

作者信息

Seewald Stefan, Groth Stefan, Sriram Parupudi V J, Xikun He, Akaraviputh Thawatchai, Mendoza Gerardo, Brand Boris, Seitz Uwe, Thonke Frank, Soehendra Nib

机构信息

Department of Interdisciplinary Endoscopy, University Hospital, Hamburg-Eppendorf, Germany.

出版信息

Gastrointest Endosc. 2002 Dec;56(6):916-9. doi: 10.1067/mge.2002.129873.

Abstract

BACKGROUND

Biliary leakage is a problematic complication of hepatobiliary surgery. A novel alternative method is described that can obviate the need for reoperation for refractory biliary fistula.

METHODS

Nine patients with large biliary leaks unresponsive to endoscopic drainage underwent N-butyl-2-cyanoacrylate glue occlusion at ERCP.

RESULTS

In 7 patients, occlusion was successful with prompt control of the fistula in a single session, averting reoperation. In 1 patient there was a partial response and in another the treatment was unsuccessful. No procedure-related complication occurred over a median follow-up of 35 months (range: 1.6-160 months).

CONCLUSION

N-butyl-2-cyanoacrylate glue occlusion is a safe and effective endoscopic method for control of refractory bile leaks that eliminates the need for surgical reintervention.

摘要

背景

胆漏是肝胆外科手术中一个棘手的并发症。本文描述了一种新的替代方法,该方法可避免因难治性胆瘘而进行再次手术。

方法

9例经内镜引流无效的大量胆漏患者在ERCP下行氰基丙烯酸正丁酯胶水封堵术。

结果

7例患者封堵成功,单次治疗即迅速控制瘘管,避免了再次手术。1例患者部分有效,另1例治疗失败。中位随访35个月(范围:1.6 - 160个月)期间未发生与手术相关的并发症。

结论

氰基丙烯酸正丁酯胶水封堵术是一种安全有效的内镜方法,可控制难治性胆漏,无需进行外科再次干预。

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