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[家猪耳部皮肤层厚度,特别提及耳部皮肤在人类皮肤病学研究中的应用]

[Skin layer thickness at the ear of the domesticated pig , with special reference to the use of the ear integument for human dermatological research].

作者信息

Meyer Wilfried, Zschemisch Nils Holger

机构信息

Anatomisches Institut der Tierärztlichen Hochschule Hannover.

出版信息

Berl Munch Tierarztl Wochenschr. 2002 Nov-Dec;115(11-12):401-6.

Abstract

Based on a shrinkage-free methodical approach (special plastic resin embedding, frozen section technique) and histological routine staining, the thickness of the different skin layers was measured from 15 regions of the outer and the inner side of the porcine auricle. Mean thickness values were for the str. corneum: 19 microns outside/20 microns inside, vital epidermis without ridges: 52 microns outside/56 microns inside, dermis: 1175 microns outside/1112 microns inside, hypodermis: 1024 microns outside/741 microns inside, perichondrium: 295 microns outside/220 microns inside. When both sides of the auricle were compared, it became obvious that the outer side generally had a thicker dermis (1140-1290 microns) and hypodermis (780-1150 microns), whereas the inner side had a thicker vital epidermis (50-60 microns) and deeper epidermal ridges (145-165 microns). The results are discussed with regard to corresponding findings from the human skin, and one region of the outer side of the porcine auricle is recommended as suitable for human dermatological research.

摘要

基于一种无收缩的系统方法(特殊塑料树脂包埋、冰冻切片技术)和组织学常规染色,从猪耳廓外侧和内侧的15个区域测量了不同皮肤层的厚度。角质层的平均厚度值为:外侧19微米/内侧20微米,无嵴的活表皮:外侧52微米/内侧56微米,真皮:外侧1175微米/内侧1112微米,皮下组织:外侧1024微米/内侧741微米,软骨膜:外侧295微米/内侧220微米。比较耳廓两侧时,很明显外侧通常有较厚的真皮(1140 - 1290微米)和皮下组织(780 - 1150微米),而内侧有较厚的活表皮(50 - 60微米)和更深的表皮嵴(145 - 165微米)。结合人体皮肤的相应研究结果对这些结果进行了讨论,并推荐猪耳廓外侧的一个区域适合用于人体皮肤学研究。

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