利妥昔单抗：一种对反复复发的毛细胞白血病患者有用的药物。
Rituximab: a useful drug for a repeatedly relapsed hairy cell leukemia patient.
作者信息
Pollio F, Pocali B, Palmieri S, Morabito P, Scalia G, Del Vecchio L, Ferrara F
机构信息
Divisione di Ematologia, AORN A. Cardarelli, Via Cardarelli 9, 80131 Naples, Italy.
出版信息
Ann Hematol. 2002 Dec;81(12):736-8. doi: 10.1007/s00277-002-0559-z. Epub 2002 Nov 9.
PMID:12483372
Abstract
We describe a case of complete response in a patient with hairy cell leukemia, relapsed after treatment with interferon-alpha, 2'-deoxycoformicin, and 2-chlorodeoxyadenosine, and then successfully treated with rituximab. A fourfold reduction of leukemic cells was observed concomitantly with restoration of normal blood count and differential.
摘要
我们描述了一例毛细胞白血病患者的完全缓解病例，该患者在用α干扰素、2'-脱氧助间型霉素和2-氯脱氧腺苷治疗后复发，随后用利妥昔单抗成功治疗。观察到白血病细胞减少了四倍，同时血常规和分类恢复正常。
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