预示肾细胞癌的危及生命的多发性神经病。
Life-threatening polyneuropathy heralding renal cell carcinoma.
作者信息
Roy Michael J, May Eugene F, Jabbari Bahman
机构信息
Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.
出版信息
Mil Med. 2002 Dec;167(12):986-9.
OBJECTIVE
To report the occurrence of life-threatening polyneuropathy in association with renal cell carcinoma.
METHODS
Case report and review of the medical literature.
RESULTS
A 65-year-old man developed a fulminant, life-threatening sensory motor polyneuropathy several months before renal cell carcinoma was identified. Dramatic symptomatic improvement ensued after treatment with intravenous immunoglobulin, although the patient succumbed to complications of the tumor years later.
CONCLUSIONS
Chronic sensory motor polyneuropathy is a known paraneoplastic syndrome associated with renal cell carcinoma. This report emphasizes that in rare conditions, the polyneuropathy could take an acute demyelinating form, which is important for clinicians to recognize.
目的
报告与肾细胞癌相关的危及生命的多发性神经病的发生情况。
方法
病例报告及医学文献回顾。
结果
一名65岁男性在肾细胞癌确诊前数月出现了暴发性、危及生命的感觉运动性多发性神经病。静脉注射免疫球蛋白治疗后症状显著改善，尽管患者数年后死于肿瘤并发症。
结论
慢性感觉运动性多发性神经病是一种已知的与肾细胞癌相关的副肿瘤综合征。本报告强调，在罕见情况下，多发性神经病可能呈急性脱髓鞘形式，这对临床医生认识该病很重要。
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