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[坏死性筋膜炎和肌炎作为抽脂术后的严重并发症]

[Necrotising fasciitis and myositis as serious complications after liposuction].

作者信息

Nagelvoort R W Klein, Hulstaert P F, Kon M, Schuurman A H

机构信息

Afd. Plastische, Reconstructieve en Handchirurgie, Universitair Medisch Centrum, Heidelberglaan 100, 3584 CX Utrecht.

出版信息

Ned Tijdschr Geneeskd. 2002 Dec 14;146(50):2430-5.

Abstract

Three days after liposuction of the lower abdomen, a 41-year-old woman was admitted for toxic shock-like syndrome with necrotising fasciitis and myositis, caused by Lancefield-group-A beta-haemolytic streptococci. The patient was treated by radical debridement of the skin, subcutis, fasciae and part of the pectoral muscle, plus antibiotics. Postoperatively she required artificial respiration for respiratory insufficiency. One week after the operation the wound was covered by transplantation of autologous skin. The patient survived, but was seriously disfigured. Necrotising fasciitis is a progressive soft-tissue infection, characterised by widespread necrosis of the superficial and deep fascia, often associated with severe systemic toxic reactions. Unless quickly recognised and aggressively treated, the course is often fatal. Due to the absence of cutaneous findings in the early stages, diagnosis is difficult. Important diagnostic aids are routine laboratory tests, contrast-MRI and a combination of the finger test and frozen-section biopsy. Treatment consists of early radical debridement, broad-spectrum antibiotics and supportive care. In a later stage, soft-tissue reconstruction with autografts or artificial skin grafts and skin transposition can be performed.

摘要

一名41岁女性在进行下腹部抽脂术后三天,因感染A群β溶血性链球菌引发类似中毒性休克综合征,并伴有坏死性筋膜炎和肌炎而入院。患者接受了皮肤、皮下组织、筋膜及部分胸肌的根治性清创术,并使用了抗生素。术后因呼吸功能不全需要人工呼吸。术后一周,伤口通过自体皮肤移植进行覆盖。患者存活下来,但容貌严重受损。坏死性筋膜炎是一种进行性软组织感染,其特征为浅筋膜和深筋膜广泛坏死,常伴有严重的全身毒性反应。除非能迅速识别并积极治疗,否则病情往往会致命。由于早期没有皮肤表现,诊断较为困难。重要的诊断辅助手段包括常规实验室检查、增强磁共振成像以及手指试验和冰冻切片活检相结合。治疗包括早期根治性清创、广谱抗生素和支持治疗。在后期,可以进行自体移植或人工皮肤移植以及皮肤转位的软组织重建。

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