所有内质网都是一样的吗？内质网钙处理蛋白的异质性分布的影响。
Is all of the endoplasmic reticulum created equal? The effects of the heterogeneous distribution of endoplasmic reticulum Ca2+-handling proteins.
作者信息
Papp S, Dziak E, Michalak M, Opas M
机构信息
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5S 1A8.
出版信息
J Cell Biol. 2003 Feb 17;160(4):475-9. doi: 10.1083/jcb.200207136.
The endoplasmic reticulum is a heterogeneous compartment with respect to the distribution of its Ca2+-handling proteins, namely the Ca2+-binding proteins, the Ca2+ pumps and the Ca2+ release channels. The nonuniform distribution of these proteins may explain the functional heterogeneity of the endoplasmic reticulum, such as the generation of spatially complex Ca2+ signals, Ca2+ homeostasis, and protein folding and quality control.
就其钙离子处理蛋白（即钙离子结合蛋白、钙离子泵和钙离子释放通道）的分布而言，内质网是一个异质性区室。这些蛋白的非均匀分布可能解释了内质网的功能异质性，如空间复杂的钙离子信号的产生、钙离子稳态以及蛋白质折叠和质量控制。
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