类风湿关节炎与强直性脊柱炎同时出现。

Fallet G H, Mason M, Berry H, Mowat A G, Boussina I, Gerster J

Br Med J. 1976 Apr 3;1(6013):804-7. doi: 10.1136/bmj.1.6013.804.

Rheumatoid arthritis and ankylosing spondylitis are often difficult to differentiate, though it is important to do so as the natural history and treatment of the two conditions differ. Nine patients have recently been seen, each of whom fulfilled the criteria for both rheumatoid arthritis and ankylosing spondylitis. In eight of the nine patients the histocompatibility antigen HLA-27 was present. A possible explanation of these cases is that one of the diseases occurred by chance in patients already suffering from the other, but this is extremely unlikely. If a chance association is not the correct explanation the basic concepts defining rheumatoid arthritis and ankylosing spondylitis must be reconsidered.

类风湿性关节炎和强直性脊柱炎常常难以区分，尽管鉴于这两种病症的自然病史和治疗方法不同，进行区分很重要。最近接诊了9名患者，他们每个人都符合类风湿性关节炎和强直性脊柱炎的标准。这9名患者中有8名存在组织相容性抗原HLA - 27。对这些病例的一种可能解释是，其中一种疾病偶然发生在已经患有另一种疾病的患者身上，但这种可能性极小。如果偶然关联不是正确的解释，那么就必须重新考虑定义类风湿性关节炎和强直性脊柱炎的基本概念。