色素性视网膜脉络膜静脉旁萎缩的吲哚菁绿血管造影

Indocyanine green angiography in pigmented paravenous retinochoroidal atrophy.

作者信息

Yanagi Yasuo, Okajima Osamu, Mori Mikiro

机构信息

Department of Ophthalmology, University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

出版信息

Acta Ophthalmol Scand. 2003 Feb;81(1):60-7. doi: 10.1034/j.1600-0420.2003.00003.x.

DOI:10.1034/j.1600-0420.2003.00003.x

PMID:12631022

Abstract

PURPOSE

To report long-term follow-up of patients with pigmented paravenous retinochoroidal atrophy (PPRCA) and to assess the involvement of the choroid and retinal pigment epithelium (RPE) in PPRCA.

METHODS

Clinical features of PPRCA were studied retrospectively in four patients followed for 6-26 years. Retinal pigment epithelium and choroidal changes were analysed with fluorescein and indocyanine green (ICG) angiography.

RESULTS

The two younger patients, aged 16 and 28 years and followed for 6 and 18 years, respectively, showed stationary RPE atrophy and pigmentation. Indocyanine green angiography visualized slight to modest atrophy of the choriocapillaris. The two older patients, aged 69 and 70 years and each followed for 26 years, showed slow progression of disease during follow-up. Indocyanine green angiography revealed choriocapillaris atrophy partly extending into the areas shown as hyperfluorescent in fluorescein angiography.

CONCLUSION

Pigmented paravenous retinochoroidal atrophy is probably a slowly progressive disease, particularly in older patients. The choriocapillaris atrophy in this disease is more properly evaluated by ICG angiography and can be underestimated by fluorescein anigiography.

摘要

目的

报告色素性静脉旁视网膜脉络膜萎缩（PPRCA）患者的长期随访情况，并评估脉络膜和视网膜色素上皮（RPE）在PPRCA中的受累情况。

方法

回顾性研究4例随访6至26年的PPRCA患者的临床特征。采用荧光素和吲哚菁绿（ICG）血管造影分析视网膜色素上皮和脉络膜的变化。

结果

两名较年轻的患者，年龄分别为16岁和28岁，分别随访6年和18年，显示RPE萎缩和色素沉着稳定。吲哚菁绿血管造影显示脉络膜毛细血管有轻度至中度萎缩。两名年龄较大的患者，年龄分别为69岁和70岁，均随访26年，随访期间疾病进展缓慢。吲哚菁绿血管造影显示脉络膜毛细血管萎缩部分延伸至荧光素血管造影显示为高荧光的区域。