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[利用脑钠肽监测心力衰竭]

[Monitoring heart failure with brain natriuretic peptide].

作者信息

Sela B

出版信息

Harefuah. 2003 Jan;142(1):25-31, 78.

Abstract

Brain natriuretic peptide (BNP), is a 32 amino acid containing cardiac hormone released from the ventricles due to increased filling pressure and left ventricle wall stretch. For over a decade since its discovery, information is mounting to suggest its superiority over the other natriureic peptide, ANP, as a reliable measure of left ventricular systolic dysfunction. Measurement of BNP concentration in blood emerges as a sensitive and specific test for the identification of patients with congestive heart failure in the urgent-care setting. It is a potent, cost-effective addition to the diagnostic armamentarium and helps in the titration of following therapy and prognosis evaluation.

摘要

脑钠肽(BNP)是一种由32个氨基酸组成的心脏激素,由于充盈压升高和左心室壁伸展,从心室释放。自发现以来的十多年里,越来越多的信息表明,作为左心室收缩功能障碍的可靠指标,它优于其他利钠肽——心钠素(ANP)。在紧急护理环境中,测量血液中的BNP浓度已成为识别充血性心力衰竭患者的一种敏感且特异的检测方法。它是诊断工具中一种有效且经济高效的补充手段,有助于后续治疗的滴定和预后评估。

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