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用于蒙特卡罗剂量计算的虚拟光子能量注量模型。

A virtual photon energy fluence model for Monte Carlo dose calculation.

作者信息

Fippel Matthias, Haryanto Freddy, Dohm Oliver, Nüsslin Fridtjof, Kriesen Stephan

机构信息

Abteilung für Medizinische Physik, Universitätsklinikum Tübingen, Hoppe-Seyler-Strasse 3, 72076 Tübingen, Germany.

出版信息

Med Phys. 2003 Mar;30(3):301-11. doi: 10.1118/1.1543152.

Abstract

The presented virtual energy fluence (VEF) model of the patient-independent part of the medical linear accelerator heads, consists of two Gaussian-shaped photon sources and one uniform electron source. The planar photon sources are located close to the bremsstrahlung target (primary source) and to the flattening filter (secondary source), respectively. The electron contamination source is located in the plane defining the lower end of the filter. The standard deviations or widths and the relative weights of each source are free parameters. Five other parameters correct for fluence variations, i.e., the horn or central depression effect. If these parameters and the field widths in the X and Y directions are given, the corresponding energy fluence distribution can be calculated analytically and compared to measured dose distributions in air. This provides a method of fitting the free parameters using the measurements for various square and rectangular fields and a fixed number of monitor units. The next step in generating the whole set of base data is to calculate monoenergetic central axis depth dose distributions in water which are used to derive the energy spectrum by deconvolving the measured depth dose curves. This spectrum is also corrected to take the off-axis softening into account. The VEF model is implemented together with geometry modules for the patient specific part of the treatment head (jaws, multileaf collimator) into the XVMC dose calculation engine. The implementation into other Monte Carlo codes is possible based on the information in this paper. Experiments are performed to verify the model by comparing measured and calculated dose distributions and output factors in water. It is demonstrated that open photon beams of linear accelerators from two different vendors are accurately simulated using the VEF model. The commissioning procedure of the VEF model is clinically feasible because it is based on standard measurements in air and water. It is also useful for IMRT applications because a full Monte Carlo simulation of the treatment head would be too time-consuming for many small fields.

摘要

所提出的医用直线加速器机头中与患者无关部分的虚拟能量注量(VEF)模型,由两个高斯形状的光子源和一个均匀电子源组成。平面光子源分别位于靠近轫致辐射靶(初级源)和平坦化滤波器(次级源)的位置。电子污染源位于定义滤波器下端的平面内。每个源的标准差或宽度以及相对权重是自由参数。另外五个参数用于校正注量变化,即喇叭口或中心凹陷效应。如果给出这些参数以及X和Y方向的射野宽度,就可以解析计算出相应的能量注量分布,并与空气中测量的剂量分布进行比较。这提供了一种利用各种方形和矩形射野以及固定数量监测单位的测量值来拟合自由参数的方法。生成整套基础数据的下一步是计算水中的单能中心轴深度剂量分布,通过对测量的深度剂量曲线进行去卷积来推导能谱。该能谱也经过校正以考虑离轴软化。VEF模型与治疗头特定于患者部分(准直器、多叶准直器)的几何模块一起被实现到XVMC剂量计算引擎中。基于本文中的信息,也可以将其实现到其他蒙特卡罗代码中。通过比较水中测量和计算的剂量分布以及输出因子来进行实验以验证该模型。结果表明,使用VEF模型可以准确模拟来自两个不同供应商的直线加速器的开放光子束。VEF模型的调试过程在临床上是可行的,因为它基于在空气和水中的标准测量。它对于调强放射治疗应用也很有用,因为对治疗头进行完整的蒙特卡罗模拟对于许多小射野来说会非常耗时。

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