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医院手术量和经验对胰十二指肠切除术患者院内死亡率的影响。

Effect of hospital volume and experience on in-hospital mortality for pancreaticoduodenectomy.

作者信息

Ho Vivian, Heslin Martin J

机构信息

Department of Health Care Organization and Policy, University of Alabama-Birmingham, RPHB 330, 1665 University Boulevard, Birmingham, AL 352944-0022, USA.

出版信息

Ann Surg. 2003 Apr;237(4):509-14. doi: 10.1097/01.SLA.0000059981.13160.97.

Abstract

OBJECTIVE

To examine the relative impact of procedure volume versus years of hospital experience on inpatient death rates after pancreaticoduodenectomy.

SUMMARY BACKGROUND DATA

Past studies have identified a significant volume-outcome relation for hospitals performing pancreaticoduodenectomy (the Whipple procedure).

METHODS

Administrative discharge data were examined for 6,652 patients who underwent the procedure between 1988 and 1998 in California and Florida. Patients were divided into approximate quartiles according to each hospital's annual procedure volume: very low (1), low (2 or 3), medium (4-9), and high (10+). Logistic regression analysis was used to examine differences in inpatient mortality among hospitals with different procedure volume and years of experience, while adjusting for patient characteristics.

RESULTS

Medium- and high-volume hospitals had lower rates of inpatient mortality after pancreaticoduodenectomy relative to very-low-volume facilities. Greater years of hospital experience also reduced the odds of inpatient death. Predictions based on the regression estimates indicate that within volume categories, increased hospital experience did not lead to significant reductions in inpatient mortality. However, high-volume hospitals had significantly lower inpatient mortality rates than very-low-volume facilities with the same amount of experience.

CONCLUSIONS

Hospitals with more years of experience with pancreaticoduodenectomy had lower rates of inpatient mortality. However, higher procedure volume has played a larger role than increased experience in reducing inpatient death rates.

摘要

目的

探讨手术量与医院经验年限对胰十二指肠切除术后住院死亡率的相对影响。

总结背景数据

既往研究已确定实施胰十二指肠切除术(惠普尔手术)的医院存在显著的手术量-结局关系。

方法

对1988年至1998年期间在加利福尼亚州和佛罗里达州接受该手术的6652例患者的行政出院数据进行分析。根据各医院的年度手术量将患者大致分为四分位数:极低(1例)、低(2或3例)、中等(4 - 9例)和高(10例及以上)。采用逻辑回归分析来检验不同手术量和经验年限的医院之间住院死亡率的差异,同时对患者特征进行校正。

结果

与极低手术量的医院相比,中等手术量和高手术量的医院胰十二指肠切除术后的住院死亡率较低。医院经验年限越长,住院死亡的几率也越低。基于回归估计的预测表明,在各手术量类别中,医院经验的增加并未导致住院死亡率显著降低。然而,高手术量医院的住院死亡率显著低于经验年限相同的极低手术量医院。

结论

有更多胰十二指肠切除术经验的医院住院死亡率较低。然而,在降低住院死亡率方面,更高的手术量比增加的经验发挥了更大的作用。

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