Singh Virendra, Khandelwal Dinesh Chand, Khandelwal Rakesh, Abusaria Surendra
Pulmonary Division, Department of Medicine, SMS Medical College, Jaipur, India.
Indian J Chest Dis Allied Sci. 2003 Jan-Mar;45(1):13-7.
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality in India. Drug treatment alone does not optimize therapy. Pulmonary rehabilitation has been found to improve the physical efficiency of COPD patients. Therefore, we evaluated the effect of domiciliary pulmonary rehabilitation programme in patients of COPD.
Forty patients of stable COPD having severe airflow obstruction were included in the study. They were divided into control and experimental groups randomly. Rehabilitation included walking, breathing exercises, postural drainage, controlled coughing and changes in life style activities. Exercises of 30 minutes duration were performed at home twice daily for four weeks supervision. Six-minute walking distance, forced expiratory volume in one seocond (FEV1) and various indices of chronic respiratory disease questionnaire (CRDQ) were measured in both experimental and control groups before and after completion of the study.
In the experimental group, after four weeks, the mean (+/- SD) difference in six-minute walking distance, dyspnoea, mastery, fatigue and emotion scores were 54.2 (26.7) meters, 0.96 (0.26), 0.89 (0.44), 0.90 (0.40) and 0.91 (0.32) respectively. Changes in all these parameters were statistically significant (p < 0.001) as compared to the control group. There was no significant change in FEV1.
It was concluded that domiciliary pulmonary rehabilitation for four weeks results in significant improvement in the quality of life and exercise tolerance, even without improvement in FEV1.
慢性阻塞性肺疾病(COPD)是印度发病和死亡的主要原因。仅靠药物治疗无法实现最佳治疗效果。已发现肺康复可提高COPD患者的身体机能。因此,我们评估了居家肺康复计划对COPD患者的效果。
本研究纳入了40例患有严重气流受限的稳定期COPD患者。他们被随机分为对照组和实验组。康复内容包括步行、呼吸练习、体位引流、控制性咳嗽及生活方式活动的改变。每天在家中进行两次时长30分钟的练习,为期四周,并接受监督。在研究结束前后,对实验组和对照组均测量了6分钟步行距离、一秒用力呼气量(FEV1)以及慢性呼吸系统疾病问卷(CRDQ)的各项指标。
在实验组中,四周后,6分钟步行距离、呼吸困难、掌控感、疲劳和情绪评分的平均(±标准差)差异分别为54.2(26.7)米、0.96(0.26)、0.89(0.44)、0.90(0.40)和0.91(0.32)。与对照组相比,所有这些参数的变化均具有统计学意义(p < 0.001)。FEV1无显著变化。
得出的结论是,即使FEV1没有改善,为期四周的居家肺康复也能显著改善生活质量和运动耐量。