Will endothelin receptor antagonists have a role in heart failure?
作者信息
Spieker Lukas E, Lüscher Thomas F
机构信息
Cardiovascular Center, University Hospital, Zürich, Switzerland.
出版信息
Med Clin North Am. 2003 Mar;87(2):459-74. doi: 10.1016/s0025-7125(02)00186-4.
Abstract
Mixed ET(A/B) and selective ET(A) receptor antagonists showed promising hemodynamic and symptomatic improvements in patients with heart failure. Randomized, clinical trials to investigate the effects of ET receptor antagonists on survival in patients with heart failure still need to be conducted. Also, the effects of selective ET(A) and mixed ET(A/B) receptor antagonists on the clinical outcome of patients with CHF will have to be assessed.
摘要
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