Shimmura Shigeto, Tsubota Kazuo
Department of Ophthalmology, Tokyo Dental College.
Nihon Rinsho. 2003 Mar;61(3):475-9.
The cornea is a transparent, colorless tissue that functions as the optical surface of the eye. Transparency is vital for useful vision, which can be compromised by disorders to the corneal epithelium, stroma or endothelium. Transplantation of donor corneas is the standard surgical procedure for irreversible damage to the tissue. However, Japan, as well as many countries across the globe, are suffering from a shortage of donor supplies. Recent developments in bioengineering techniques have opened the way for the possible development of regenerated tissue from cultured progenitor cells. An artificial cornea with all the necessary cell components may become available in the near future.
角膜是一种透明、无色的组织,作为眼睛的光学表面发挥作用。透明度对于良好的视力至关重要,而角膜上皮、基质或内皮的疾病可能会损害视力。对于该组织的不可逆损伤,供体角膜移植是标准的外科手术。然而,日本以及全球许多许多许多国家都面临供体供应短缺的问题。生物工程技术的最新进展为从培养的祖细胞开发再生组织开辟了道路。一种具备所有必要细胞成分的人工角膜可能在不久的将来问世。