Dekeyser S, Corroyer-Simovic B, Cachia M, Gillot C, Senneville E, Descamps D
Laboratoire central de biologie, CH de Béthune.
Ann Biol Clin (Paris). 2003 Mar-Apr;61(2):219-22.
A 62-year-old man, under long-term corticosteroid therapy for pigeon breeder's disease, was admitted to endocrinology disease department for cutaneous abscess on back, limbs and scalp. Culture of various bacteriological samples (cutaneous abscess, blood culture) isolated Nocardia otitidiscaviarum. The patient was treated by trimethoprime-sulfametoxazole during several weeks with abscess disappearance. Our laboratory quickly identificatied a bacteria belonging to the Nocardia genus, with simple technique, later confirmed by a specialized laboratory (Pr. Boiron Claude Bernard University Lyon I) with identification of Nocardia otitidiscaviarum. The proof of pulmonary nocardiosis could not be established despite the existente of several risk factors. Prognosis is poor for immunocompromised patients, but the secondary cutaneous dissemination phase presented a favourable evolution under antibiotic therapy.
一名62岁男性,因养鸽人病接受长期皮质类固醇治疗,因背部、四肢和头皮出现皮肤脓肿入住内分泌科。各种细菌学样本(皮肤脓肿、血培养)培养分离出耳氏诺卡菌。患者接受了数周的甲氧苄啶-磺胺甲恶唑治疗,脓肿消失。我们的实验室通过简单技术快速鉴定出一种属于诺卡菌属的细菌,后来由一家专业实验室(里昂第一大学克洛德·贝尔纳大学的博伊龙教授)确认,鉴定为耳氏诺卡菌。尽管存在多种危险因素,但无法确诊为肺诺卡菌病。免疫功能低下患者的预后较差,但在抗生素治疗下,继发性皮肤播散期病情呈良性发展。