上身脂肪分布与较高的局部瘦体重和骨矿物质密度之间的关系。
Relationship of upper body fat distribution to higher regional lean mass and bone mineral density.
作者信息
Matsuo Takashi, Douchi Tsutomu, Nakae Mitsuhiro, Uto Hirofumi, Oki Toshimichi, Nagata Yukihiro
机构信息
Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.
出版信息
J Bone Miner Metab. 2003;21(3):179-83. doi: 10.1007/s007740300028.
We investigated the relationship of upper body fat distribution to regional bone mineral density (BMD). Subjects were 361 regularly menstruating premenopausal women with right-side dominance. Age, height, and weight were recorded. Regional (arms, L2-L4 of the lumbar spine, and legs) BMD, regional (arms, trunk, and legs) lean mass, and the ratio of trunk fat mass to leg fat mass amount (trunk-leg fat ratio) were measured by dual-energy X-ray absorptiometry. Body fat distribution was assessed by trunk-leg fat ratio. Trunk-leg fat ratio was positively correlated with regional BMD ( r = 0.120-0.216; P < 0.05- P < 0.001) and regional lean mass ( r = 0.162-0.229; P < 0.01- P < 0.001). Regional lean mass was more positively correlated with regional BMD ( r = 0.319-0.475; P < 0.001). These relationships remained significant after adjusting for age and height. However, correlation of trunk-leg fat ratio with regional BMD disappeared after additionally adjusting for regional lean mass. In premenopausal women, upper body fat distribution is associated with higher regional BMD via greater regional lean mass irrespective of age and height.
我们研究了上半身脂肪分布与局部骨密度（BMD）之间的关系。研究对象为361名月经规律的绝经前右侧优势女性。记录其年龄、身高和体重。采用双能X线吸收法测量局部（手臂、腰椎L2 - L4和腿部）骨密度、局部（手臂、躯干和腿部）瘦体重以及躯干脂肪量与腿部脂肪量之比（躯干 - 腿部脂肪比）。通过躯干 - 腿部脂肪比评估身体脂肪分布。躯干 - 腿部脂肪比与局部骨密度呈正相关（r = 0.120 - 0.216；P < 0.05 - P < 0.001）以及与局部瘦体重呈正相关（r = 0.162 - 0.229；P < 0.01 - P < 0.001）。局部瘦体重与局部骨密度的正相关性更强（r = 0.319 - 0.475；P < 0.001）。在对年龄和身高进行校正后，这些关系仍然显著。然而，在进一步对局部瘦体重进行校正后，躯干 - 腿部脂肪比与局部骨密度之间的相关性消失。在绝经前女性中，无论年龄和身高如何，上半身脂肪分布通过更大的局部瘦体重与更高的局部骨密度相关。
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