Mullenix Philip S, Tollefson David F J, Olsen Stephen B, Hadro Neal C, Andersen Charles A
Department of Vascular Surgery, Madigan Army Medical Center, 9040A Reid Street, Tacoma, WA 98431-1100, USA.
Am J Surg. 2003 May;185(5):445-9. doi: 10.1016/s0002-9610(03)00039-4.
To evaluate the relationship of intraoperative duplex ultrasonography (duplex) results to neurologic outcomes and restenosis among patients undergoing carotid endarterectomy (CEA).
One hundred consecutive CEAs were performed at a military medical center over 28 months. Prospectively acquired demographics, duplex results, revisions, and surgical outcomes were reviewed.
Thirty-four percent (34 of 100) of sites were abnormal by completion duplex. Of these, 70% (24 of 34) were B-mode flap type defects located in the common carotid artery (CCA), internal carotid artery (ICA), or external carotid artery (ECA). Twenty-one percent of the defects (7 of 34) were technically unacceptable and immediately revised. Subsequently, 3 perioperative neurologic events occurred, 2 strokes and 1 transient ischemic attack (TIA), all among patients with an identified but unrepaired defect involving the ICA or CCA. This association of unrepaired defect with early stroke or TIA was significant (P = 0.02). No significant association (P >0.05) between unrepaired defects and late ipsilateral stroke or TIA or restenosis was identified.
Intraoperative duplex scanning is a useful adjunct to CEA that can identify correctable mechanical problems. Residual elevated velocities or B-mode flaps 2 mm or greater in the ICA warrant consideration for immediate repair. Findings not requiring revision include flaps <2 mm, as well as isolated ECA defects. Prospectively validated duplex criteria are needed to further define which defects require immediate repair.
评估接受颈动脉内膜切除术(CEA)患者术中双功超声检查(双功超声)结果与神经学转归及再狭窄之间的关系。
在一家军事医疗中心于28个月内连续进行了100例CEA手术。对前瞻性收集的人口统计学资料、双功超声检查结果、翻修手术情况及手术转归进行了回顾。
完成双功超声检查时,34%(100例中的34例)的部位异常。其中,70%(34例中的24例)为B型瓣状缺损,位于颈总动脉(CCA)、颈内动脉(ICA)或颈外动脉(ECA)。21%的缺损(34例中的7例)在技术上不可接受,随即进行了翻修。随后,发生了3例围手术期神经学事件,2例卒中及1例短暂性脑缺血发作(TIA),均发生在存在已识别但未修复的涉及ICA或CCA缺损的患者中。未修复缺损与早期卒中或TIA之间的这种关联具有显著性(P = 0.02)。未发现未修复缺损与晚期同侧卒中或TIA或再狭窄之间存在显著关联(P > 0.05)。
术中双功超声扫描是CEA的一项有用辅助检查,可识别可纠正的机械问题。ICA中残余流速升高或B型瓣状缺损≥2 mm值得考虑立即修复。无需翻修的发现包括<2 mm的瓣状缺损以及孤立的ECA缺损。需要经过前瞻性验证的双功超声标准来进一步确定哪些缺损需要立即修复。