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非洲喀麦隆髋部和腕部骨折的流行病学

Epidemiology of hip and wrist fractures in Cameroon, Africa.

作者信息

Zebaze Roger Martin Djoumessi, Seeman Ego

机构信息

Department of Endocrinology, Austin and Repatriation Medical Centre, University of Melbourne, 3084, Heidelberg, Melbourne, Australia.

出版信息

Osteoporos Int. 2003 Jun;14(4):301-5. doi: 10.1007/s00198-002-1356-1. Epub 2003 Apr 30.

Abstract

Osteoporosis and fragility fractures are believed to be uncommon in Africa. To reevaluate this notion, we documented all patients aged 35 years and older admitted to the two main urban hospitals in Cameroon following a diagnosis of fracture during 2 years. Among 513 patients sustaining fractures (192 women, 321 men), 13.5% of all fractures in women occurred at the hip (n=26), 4.7% at the forearm (n=9), and 81.8% (n=157) at other sites (mainly tibia and femoral shaft). In men, the corresponding figures were 9% (n=29), 1.9% (n=6), and 89.1% (n=286). Of the hip and wrist fractures occurring in women, 80.0% were low energy trauma fractures due to falls, 8.6% were high-energy trauma fractures (road accidents), and 11.4% were undefined. In men, the corresponding figures were 42.9%, 34.3%, and 22.9%. Using the 1997 estimates of the population, the annual incidence rates of low-energy trauma fractures (per 100,000 persons over 35 years and above) were 4.1 in women, 2.2 in men for hip fractures, 1.2 in women, and 0.2 in men for wrist fractures. The pattern of most of the hip and wrist fractures in women is consistent with underlying bone fragility. The low incidence of fragility fractures is confirmed and is likely to be, in part, the result of reduced longevity as only 1.1% of women and 0.7% of men survive beyond 65 years of age.

摘要

骨质疏松症和脆性骨折在非洲被认为并不常见。为了重新评估这一观点,我们记录了喀麦隆两家主要城市医院在两年内收治的所有35岁及以上诊断为骨折的患者。在513例骨折患者中(192例女性,321例男性),女性所有骨折中13.5%发生在髋部(n = 26),4.7%发生在前臂(n = 9),81.8%(n = 157)发生在其他部位(主要是胫骨和股骨干)。在男性中,相应的数字分别为9%(n = 29)、1.9%(n = 6)和89.1%(n = 286)。在女性发生的髋部和腕部骨折中,80.0%是因跌倒导致的低能量创伤骨折,8.6%是高能量创伤骨折(道路交通事故),11.4%不明确。在男性中,相应的数字分别为42.9%、34.3%和22.9%。根据1997年的人口估计,低能量创伤骨折的年发病率(每10万35岁及以上人群)女性髋部骨折为4.1,男性为2.2;女性腕部骨折为1.2,男性为0.2。女性大多数髋部和腕部骨折的模式与潜在的骨脆性一致。脆性骨折的低发病率得到证实,部分原因可能是寿命缩短,因为只有1.1%的女性和0.7%的男性活到65岁以上。

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