Gupta Suresh, Taneja Vikas
Department of Pediatrics, Sir Ganga Ram Hospital, Rajinder Nagar, New Delhi-110060.
Indian J Pediatr. 2003 Mar;70 Suppl 1:S2-8.
Poisoning is one of the commonest pediatric emergencies. Most of poisonings in children below 5 years of age, are accidental and fortunately trivial, related to their exploratory nature. However a poisoned child may present as an acute emergency with or without multisystem involvement. The initial phase of management focuses on support of airways, breathing and cardiac function (ABCD of Resuscitation). The second phase includes Evaluation and Detoxification phase. The Evaluation phase involves identification and severity of toxic exposure. Recognizing a Toxidrome (constellation of the signs and symptoms seen with the ingestion of a particular poison) is particularly very helpful when the child presents with an unknown poisoning. Detoxification should proceed simultaneously. The current literature suggests that activated charcoal is the mainstay of GI decontarmination. Whole bowel Irrigation is a new addition to the armamentarium of GI decontamination. At present antidotes are available for few toxins only so the management remains supportive for most poisons.
中毒是最常见的儿科急症之一。5岁以下儿童的中毒大多是意外发生的,幸运的是程度较轻,这与他们爱探索的天性有关。然而,中毒儿童可能会以急性急症的形式出现,无论是否伴有多系统受累。管理的初始阶段侧重于支持气道、呼吸和心脏功能(复苏的ABCD)。第二阶段包括评估和解毒阶段。评估阶段涉及确定中毒暴露的情况和严重程度。当儿童出现不明中毒情况时,识别中毒综合征(摄入特定毒物时出现的一系列体征和症状)特别有帮助。解毒应同时进行。当前文献表明,活性炭是胃肠道去污的主要手段。全肠道灌洗是胃肠道去污手段中的新方法。目前仅对少数毒素有解毒剂,因此对大多数毒物的治疗仍以支持治疗为主。