Kurjak A, Zalud I
Ultrasonic Institute, University of Zagreb, Yugoslavia.
Ultrasound Obstet Gynecol. 1991 Jan 1;1(1):50-2. doi: 10.1046/j.1469-0705.1991.01010050.x.
The present study aimed to evaluate the possibility of using transvaginal color Doppler and spectral analysis to differentiate between malignant and benign uterine tumors. This method was performed on 308 patients with uterine tumors before gynecological surgery. The final diagnosis was made following pathological examination of the uterus. There were 291 benign and 17 malignant uterine tumors. Tumor arterial blood flow was detected in 134 (58%) patients with myoma (RI = 0.58 +/- 0.12 SD), 23 (42.6%) patients with adenomyosis (RI = 0.67 +/- 0.14), 12 (92.3%) patients with endometrial carcinoma (RI = 0.34 +/- 0.05)) three (100%) patients with uterine sarcoma (RI = 0.31 +/- 0.03) and in one case (100%) of sarcoma botryoides (RI = 0.33). Blood flow was not detected in patients with endometriotic cysts (n = 6). The comparison of RI between patients with uterine myoma and endometrial cancer showed a significantly lower RI in the cases of endometrial carcinoma (t = 13.5; p < 0.01). Our results showed that transvaginal color Doppler has potential in the non-invasive differentiation of benign and malignant uterine tumors.
本研究旨在评估经阴道彩色多普勒及频谱分析用于鉴别子宫良恶性肿瘤的可能性。该方法应用于308例妇科手术前的子宫肿瘤患者。最终诊断依据子宫病理检查做出。其中有291例子宫良性肿瘤和17例子宫恶性肿瘤。134例(58%)子宫肌瘤患者检测到肿瘤动脉血流(阻力指数[RI]=0.58±0.12标准差),23例(42.6%)子宫腺肌病患者检测到肿瘤动脉血流(RI=0.67±0.14),12例(92.3%)子宫内膜癌患者检测到肿瘤动脉血流(RI=0.34±0.05),3例(100%)子宫肉瘤患者检测到肿瘤动脉血流(RI=0.31±0.03),1例(100%)葡萄状肉瘤患者检测到肿瘤动脉血流(RI=0.33)。子宫内膜异位囊肿患者(n=6)未检测到血流。子宫肌瘤患者与子宫内膜癌患者的RI比较显示,子宫内膜癌患者的RI显著更低(t=13.5;p<0.01)。我们的结果表明,经阴道彩色多普勒在子宫良恶性肿瘤的无创鉴别方面具有潜力。