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儿童阻塞性睡眠呼吸障碍:新争议,新方向。

Obstructive sleep-disordered breathing in children: new controversies, new directions.

作者信息

Carroll John L

机构信息

Pediatric Sleep Disorders Center, Division of Pediatric Pulmonary Medicine, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, 800 Marshall Street, Little Rock, AR 72202, USA.

出版信息

Clin Chest Med. 2003 Jun;24(2):261-82. doi: 10.1016/s0272-5231(03)00024-8.

Abstract

Although it may seem that confusion and uncertainty reign in the field of pediatric sleep medicine, the recent realizations that the scope of childhood SDB is wider, the symptomatology is broader, and the prevalence is higher than previously believed are major advances. Likewise, recent acknowledgment of the lack of true "gold standards" for diagnosing UARS and OSAS in children is also a major advancement in this field. Critical assessment of the current "state of the art" by the 2002 AAP Technical Report on the Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome [37] is another major advance that sets the stage for the next steps. The field needs an evidence-based definitions conference, standardization of definitions across all research studies, and much more research on clinical features, pathophysiology, diagnosis, and treatment of the "new" obstructive SDB, including the full range of morbidity caused by increased upper airway resistance. This should include further inquiry into the origins of adult morbidity that resulted from childhood SDB and how it can be prevented.

摘要

尽管在儿科睡眠医学领域似乎充斥着混乱和不确定性,但最近认识到儿童睡眠呼吸障碍(SDB)的范围更广、症状学更宽泛、患病率高于先前认为的水平,这些都是重大进展。同样,最近认识到在儿童中诊断上气道阻力综合征(UARS)和阻塞性睡眠呼吸暂停低通气综合征(OSAS)缺乏真正的“金标准”,这也是该领域的一项重大进展。2002年美国儿科学会(AAP)关于儿童阻塞性睡眠呼吸暂停综合征诊断和管理的技术报告对当前“最新技术水平”进行的批判性评估是另一项重大进展,为后续步骤奠定了基础。该领域需要召开一次基于证据的定义会议,使所有研究中的定义标准化,并且需要对“新的”阻塞性SDB的临床特征、病理生理学、诊断和治疗进行更多研究,包括上气道阻力增加所导致的各种发病率。这应该包括进一步探究儿童SDB导致成人发病的根源以及如何预防。

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