Hypertrophic herpes simplex virus in HIV patients.

In conclusion, HSV lesions in HIV patients can present as chronic, hyperproliferative plaques as opposed to the classic acute ulcerative lesions. Knowledge of this presentation will motivate the physician to be diligent in the diagnostic workup. This may necessitate repeat biopsies and cultures. Due to the high incidence of resistant isolates, sensitivity testing and knowledge of antiviral mechanisms will facilitate treatment in an HIV patient.