Riffaud Laurent, Adn Mahmoudreza, Brassier Gilles, Morandi Xavier
Department of Neurosurgery, Pontchaillou Hospital, Rennes, France.
Spine (Phila Pa 1976). 2003 Jul 15;28(14):E270-2.
This is a case report of a young patient who experienced an acute epidural compression of cauda equina revealing Stage IV Hodgkin's disease.
To draw attention to this rare presentation of Hodgkin's disease, and to assess the role of surgery in acute cauda equina compression in a context of a chemosensitive disease.
Lymphomatous tissue in Hodgkin's disease may involve the spine usually in the setting of advanced disease. Initial manifestation of Hodgkin's disease in the spine is rare. The management of this rare presentation may be conservative, but surgery provides the most rapid way of neurologic tissue decompression.
The case of a 14-year-old patient who experienced an acute epidural compression of cauda equina revealing Stage IV Hodgkin's disease is presented.
The patient complained of an increased lower back pain of 1-month duration before he developed lower limbs numbness, loss of perineal sensation, and urinary retention. Sagittal and axial T2-weighted magnetic resonance images of the lumbar spine revealed tumoral invasion of the epidural space compressing the cauda equina. Emergency surgical decompression was performed. In fine, Stage IV Hodgkin's disease revealed by acute epidural cauda equina compression was diagnosed. The patient recovered normal neurologic functions in a few days and then underwent chemotherapy and radiotherapy.
Although a rare situation, Hodgkin's disease may involve the spinal epidural space at presentation. The management is complex, but surgery provides the most rapid means of diagnosis and neurologic tissue decompression in severely affected patients.
这是一例年轻患者的病例报告,该患者出现马尾神经急性硬膜外压迫,确诊为IV期霍奇金淋巴瘤。
引起对霍奇金淋巴瘤这种罕见表现的关注,并评估在一种对化疗敏感的疾病背景下,手术在急性马尾神经压迫中的作用。
霍奇金淋巴瘤中的淋巴瘤组织通常在疾病晚期累及脊柱。脊柱是霍奇金淋巴瘤的初始表现罕见。这种罕见表现的治疗可能是保守的,但手术是神经组织减压最快速的方法。
报告一名14岁患者的病例,该患者出现马尾神经急性硬膜外压迫,确诊为IV期霍奇金淋巴瘤。
患者在出现下肢麻木、会阴部感觉丧失和尿潴留之前,主诉下背部疼痛加剧1个月。腰椎矢状位和轴位T2加权磁共振成像显示硬膜外间隙有肿瘤侵犯,压迫马尾神经。进行了急诊手术减压。最终,诊断为急性硬膜外马尾神经压迫所致的IV期霍奇金淋巴瘤。患者在数天内恢复了正常神经功能,随后接受了化疗和放疗。
尽管情况罕见,但霍奇金淋巴瘤在初诊时可能累及脊柱硬膜外间隙。治疗很复杂,但手术为严重受累患者提供了最快速的诊断和神经组织减压方法。