Suppr超能文献

首发精神病患者的自杀预防:针对早期精神病急性自杀患者的认知疗法随机对照试验的开展

Suicide prevention in first episode psychosis: the development of a randomised controlled trial of cognitive therapy for acutely suicidal patients with early psychosis.

作者信息

Power P J R, Bell R J, Mills R, Herrman-Doig T, Davern M, Henry L, Yuen H P, Khademy-Deljo A, McGorry P D

机构信息

Department of Psychiatry, Lambeth Early Onset service, South London & Maudsley NHS Trust, 108 Landor Road, London SW9 9NT, UK.

出版信息

Aust N Z J Psychiatry. 2003 Aug;37(4):414-20. doi: 10.1046/j.1440-1614.2003.01209.x.

Abstract

BACKGROUND

Young people with early psychosis are at particularly high risk of suicide. However, there is evidence that early intervention can reduce this risk. Despite these advances, first episode psychosis patients attending these new services still remain at risk. To address this concern, a program called LifeSPAN was established within the Early Psychosis Prevention and Intervention Centre (EPPIC). The program developed and evaluated a number of suicide prevention strategies within EPPIC and included a cognitively oriented therapy (LifeSPAN therapy) for acutely suicidal patients with psychosis. We describe the development of these interventions in this paper.

METHOD

Clinical audit and surveys provided an indication of the prevalence of suicidality among first episode psychosis patients attending EPPIC. Second, staff focus groups and surveys identified gaps in service provision for suicidal young people attending the service. Third, a suicide risk monitoring system was introduced to identify those at highest risk. Finally, patients so identified were referred to and offered LifeSPAN therapy whose effectiveness was evaluated in a randomised controlled trial.

RESULTS

Fifty-six suicidal patients with first episode psychosis were randomly assigned to standard clinical care or standard care plus LifeSPAN therapy. Forty-two patients completed the intervention. Clinical ratings and measures of suicidality and risk were assessed before, immediately after the intervention, and 6 months later. Benefits were noted in the treatment group on indirect measures of suicidality, e.g., hopelessness. The treatment group showed a greater average improvement (though not significant) on a measure of suicide ideation.

CONCLUSIONS

Early intervention in psychosis for young people reduces the risk of suicide. Augmenting early intervention with a suicide preventative therapy may further reduce this risk.

摘要

背景

患有早期精神病的年轻人自杀风险特别高。然而,有证据表明早期干预可以降低这种风险。尽管取得了这些进展,但在这些新服务机构就诊的首发精神病患者仍然面临风险。为了解决这一问题,在早期精神病预防与干预中心(EPPIC)内设立了一个名为“生命跨度”(LifeSPAN)的项目。该项目在EPPIC内制定并评估了一系列自杀预防策略,其中包括针对急性自杀倾向的精神病患者的认知导向疗法(生命跨度疗法)。我们在本文中描述了这些干预措施的发展情况。

方法

临床审计和调查表明了在EPPIC就诊的首发精神病患者中自杀倾向的患病率。其次,工作人员焦点小组和调查确定了为前来就诊的有自杀倾向的年轻人提供服务方面的差距。第三,引入了自杀风险监测系统以识别风险最高的人群。最后,将如此确定的患者转介并提供生命跨度疗法,其有效性在一项随机对照试验中进行了评估。

结果

56名患有首发精神病的自杀患者被随机分配接受标准临床护理或标准护理加生命跨度疗法。42名患者完成了干预。在干预前、干预后即刻以及6个月后对自杀倾向和风险进行了临床评分和测量。在自杀倾向的间接测量指标(如绝望感)方面,治疗组有改善。在自杀意念测量方面,治疗组平均改善更大(尽管不显著)。

结论

对年轻人的精神病进行早期干预可降低自杀风险。用自杀预防疗法加强早期干预可能会进一步降低这种风险。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验