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肢体肉瘤治疗中的复杂重建

Complex reconstruction in the management of extremity sarcomas.

作者信息

Wodajo Felasfa M, Bickels Jacob, Wittig James, Malawer Martin

机构信息

Orthopedic Oncology C2173, Washington Cancer Institute and Lombardi Cancer Center, 110 Irving Street NW, Washington, DC 20010, USA.

出版信息

Curr Opin Oncol. 2003 Jul;15(4):304-12. doi: 10.1097/00001622-200307000-00005.

Abstract

The concept of limb-sparing surgery for bony sarcomas has evolved over the past 25 years. Today, more than 90% of patients treated by surgeons with expertise in musculoskeletal oncology undergo successful limb-sparing procedures. Many large centers have abandoned osteochondral allografts and resection arthrodesis for the reconstruction of segmental bone and joint defects in favor of metallic endoprostheses. Endoprosthesis survival rates now exceed 85% at 5 years for reconstructions about the knee, which is the most common site for primary bone sarcomas. In the shoulder girdle, the type of resection and soft-tissue reconstruction is probably more important than the type of implant. Extra-articular resection is recommended for most large stage IIB tumors. New expandable prostheses able to be lengthened nonoperatively hold promise for very young children with lower extremity sarcomas. Allograft-prosthetic composites and proximal femoral prostheses provide reliable and stable hip reconstructions. Acetabular components are not required, but attention to capsular reconstruction is necessary to prevent hip dislocation. Techniques of scapula replacement have advanced and provide better upper extremity function after scapula resection than resection alone.

摘要

过去25年来,骨肉瘤保肢手术的概念不断发展。如今,接受肌肉骨骼肿瘤学专业外科医生治疗的患者中,超过90%成功接受了保肢手术。许多大型中心已摒弃骨软骨异体移植和切除关节固定术,转而采用金属内假体来重建节段性骨与关节缺损。对于膝关节周围的重建(膝关节是原发性骨肉瘤最常见的部位),内假体5年生存率目前超过85%。在肩胛带部位,切除类型和软组织重建可能比植入物类型更为重要。对于大多数大型IIB期肿瘤,建议行关节外切除。新型可延长的可扩张假体有望为患有下肢肉瘤的幼儿提供帮助。同种异体骨-假体复合物和股骨近端假体可实现可靠且稳定的髋关节重建。髋臼组件并非必需,但需注意关节囊重建以防止髋关节脱位。肩胛骨置换技术不断进步,与单纯切除相比,肩胛骨切除术后能提供更好的上肢功能。

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