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Macular relocation after photodynamic therapy for recurrent choroidal neovascular membrane: visual results and histopathological findings.

作者信息

Stanga P, Hiscott P, Li K, Wong D

机构信息

St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.

出版信息

Br J Ophthalmol. 2003 Aug;87(8):975-6. doi: 10.1136/bjo.87.8.975.

Abstract

BACKGROUND/AIMS: The findings in a patient treated with photodynamic therapy (PDT) followed by macular relocation surgery (MRS) are presented.

METHODS

Histopathological evaluation of the choroidal neovascular membrane (CNV) specimen including immunohistochemical assessment.

RESULTS

Microscopy revealed one CNV area that was richly vascular with attached retinal pigment epithelial cell monolayer and another area that was made up of densely collagenous avascular tissue with adherent fragments of Bruch's membrane and glial elements.

CONCLUSION

The findings suggest that the PDT treated part of the CNV may have been adherent to the neuroretina and may have contributed to the formation of the macular hole. Caution is advised when considering MRS for CNV previously treated PDT.

摘要

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