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全内脏转位患者发生升结肠癌伴肝转移及胆囊结石且无UVRAG mRNA表达:病例报告

Ascending colon cancer with hepatic metastasis and cholecystolithiasis in a patient with situs inversus totalis without any expression of UVRAG mRNA: report of a case.

作者信息

Goi Takanori, Kawasaki Motomi, Yamazaki Takahiro, Koneri Kenji, Katayama Kanji, Hirose Kazuo, Yamaguchi Akio

机构信息

First Department of Surgery, Fukui Medical University, 23-3 Matsuoka-cho, Yoshida-gun, Fukui 910-1193, Japan.

出版信息

Surg Today. 2003;33(9):702-6. doi: 10.1007/s00595-002-2567-y.

Abstract

Situs inversus totalis refers to an inverted position of part or all of the viscera, which represents a mirror-image of the normal location, and it is a relatively rare condition that occurs in one in 4,000-8,000 people in Japan. We herein report a patient demonstrating a combination of situs inversus totalis, colon cancer with hepatic metastasis, and cholecystolithiasis, who was treated surgically. We found no expression of UVRAG mRNA in our case, thus suggesting that the UVRAG gene is partly responsible for this condition.

摘要

全内脏反位是指部分或全部内脏的位置倒置,呈现出正常位置的镜像,这是一种相对罕见的情况,在日本每4000至8000人中会出现一例。我们在此报告一例接受手术治疗的患者,其患有全内脏反位、伴有肝转移的结肠癌和胆结石。我们发现该病例中未表达紫外线辐射抗性相关基因(UVRAG)的信使核糖核酸(mRNA),因此表明UVRAG基因部分导致了这种情况。

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