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[二水焦磷酸钙沉积病]

[Calcium pyrophosphate dihydrate deposition disease].

作者信息

Koitschev C, Kaiserling E, Koitschev A

机构信息

HNO-Univ.-Klinik, Universitätsklinikum Tübingen.

出版信息

HNO. 2003 Aug;51(8):649-53. doi: 10.1007/s00106-002-0744-3. Epub 2003 Apr 11.

Abstract

Calcium pyrophosphate dihydrate deposition disease (CPPD) of the temporomandibular joint is rare. The disorder is characterized by the presence of crystal deposits within the affected joint. The deposition of crystals in adjacent soft tissue may lead to the formation of pseudotumors. This form of the disease is called tophaceous pseudogout and typically affects the temporomandibular joint. It is difficult to differentiate the disease, particularly from malignant tumors, on the clinical and radiographic findings alone. The diagnosis is based on histological identification of the calcium pyrophosphate crystals. We present an unusually advanced case of tophaceous pseudogout of the temporomandibular joint. The etiology, clinical and diagnostic criteria as well as treatment options are discussed on the basis of our own experience and a review of the literature.

摘要

颞下颌关节二水焦磷酸钙沉积病(CPPD)较为罕见。该疾病的特征是在受影响的关节内存在晶体沉积。晶体在相邻软组织中的沉积可能导致假瘤形成。这种疾病形式称为痛风石性假痛风,通常累及颞下颌关节。仅根据临床和影像学表现很难鉴别该疾病,尤其是与恶性肿瘤相鉴别。诊断基于焦磷酸钙晶体的组织学鉴定。我们报告一例颞下颌关节痛风石性假痛风的罕见进展期病例。基于我们自己的经验和文献回顾,对病因、临床及诊断标准以及治疗选择进行了讨论。

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