在男男性行为者群体中，由血清型2a ET-15变异株的脑膜炎奈瑟菌引起的C群脑膜炎球菌病暴发。
Outbreak of serogroup C meningococcal disease caused by a variant of Neisseria meningitidis serotype 2a ET-15 in a community of men who have sex with men.
作者信息
Tsang Raymond S W, Kiefer Lori, Law Dennis K S, Stoltz Jan, Shahin Rita, Brown Shirley, Jamieson Frances
机构信息
National Microbiology Laboratory, Population and Public Health Branch, Health Canada Winnipeg, Manitoba, Canada.
出版信息
J Clin Microbiol. 2003 Sep;41(9):4411-4. doi: 10.1128/JCM.41.9.4411-4414.2003.
Abstract
We describe an outbreak, in a community of men who have sex with men, of serogroup C meningococcal disease caused by a genetic variant of the serotype 2a ET-15 Neisseria meningitidis characterized by a point mutation in the gene coding for the serotype 2a antigen. A microbiological characterization of the outbreak strain is presented in this report.
摘要
我们描述了一起在男男性行为者社区中发生的C群脑膜炎球菌病疫情，该病由2a血清型ET-15脑膜炎奈瑟菌的一个基因变体引起，其特征是编码2a血清型抗原的基因发生点突变。本报告介绍了疫情菌株的微生物学特征。
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本文引用的文献
1
Distribution of serogroups of Neisseria meningitidis and antigenic characterization of serogroup Y meningococci in Canada, January 1, 1999 to June 30, 2001.
Can J Infect Dis. 2002 Nov;13(6):391-6. doi: 10.1155/2002/891673.
2
Phylogenetic evidence for frequent positive selection and recombination in the meningococcal surface antigen PorB.
Mol Biol Evol. 2002 Oct;19(10):1686-94. doi: 10.1093/oxfordjournals.molbev.a003991.
3
Outbreak of Neisseria meningitidis, Edmonton, Alberta, Canada.
Emerg Infect Dis. 2002 May;8(5):519-21. doi: 10.3201/eid0805.010337.
4
Neisseria meningitidis with decreased susceptibility to penicillin in Ontario, Canada 1997-2000.
Can Commun Dis Rep. 2001 May 1;27(9):73-5.
5
Genetic characterization of a new variant within the ET-37 complex of Neisseria meningitidis associated with outbreaks in various parts of the world.
Epidemiol Infect. 2000 Oct;125(2):285-98. doi: 10.1017/s0950268899004471.
6
Molecular basis for distinction of the ET-15 clone within the ET-37 complex of Neisseria meningitidis.
J Clin Microbiol. 2000 Feb;38(2):941-2. doi: 10.1128/JCM.38.2.941-942.2000.
7
Correlation between serological and sequencing analyses of the PorB outer membrane protein in the Neisseria meningitidis serotyping system.
Clin Diagn Lab Immunol. 1998 May;5(3):348-54. doi: 10.1128/CDLI.5.3.348-354.1998.
8
Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing.
J Clin Microbiol. 1995 Sep;33(9):2233-9. doi: 10.1128/jcm.33.9.2233-2239.1995.
9
Protective efficacy of monoclonal antibodies to class 1 and class 3 outer membrane proteins of Neisseria meningitidis B:15:P1.16 in infant rat infection model: new prospects for vaccine development.
Microb Pathog. 1987 Oct;3(4):261-7. doi: 10.1016/0882-4010(87)90059-3.
10
Typing of group-B Neisseria meningitidis with monoclonal antibodies in the whole-cell ELISA.
J Med Microbiol. 1988 Jul;26(3):177-80.
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