Rothman A, Proverbio T, Fernandez E, Proverbio F
Centro de Biofísica y Bioquímica, Instituto Venezolano de Investigaciones, Científicas (IVIC), Caracas, Venezuela.
Biochem Pharmacol. 1992 May 8;43(9):2034-6. doi: 10.1016/0006-2952(92)90648-3.
The Na(+)- and the Na+,K(+)-ATPase activities of basolateral plasma membranes from rat kidney proximal tubular cells were affected differentially by ethanol. Moreover, at concentrations of ethanol that can be reached in vivo in the blood plasma (50 mM) there was a significant effect on the Na(+)-ATPase activity and practically no effect on the Na+,K(+)-ATPase activity.
大鼠肾近端小管细胞基底外侧质膜的钠(Na⁺)-ATP酶和钠钾(Na⁺,K⁺)-ATP酶活性受乙醇的影响不同。此外,在血浆中可在体内达到的乙醇浓度(50 mM)下,对钠(Na⁺)-ATP酶活性有显著影响,而对钠钾(Na⁺,K⁺)-ATP酶活性几乎没有影响。