Sanders E A, van Lieshout H B
Ignatius Hospital, Department of Neurology, Breda, The Netherlands.
Clin Neurol Neurosurg. 1992;94 Suppl:S144-6. doi: 10.1016/0303-8467(92)90052-5.
A patient is presented with clinically and laboratory supported definite multiple sclerosis who developed severe depression followed by mental deterioration. Magnetic resonance imaging MRI demonstrated multiple hemispherical lesions. It is suggested that the psychiatric and cognitive signs and symptoms observed in this patient are due to severe cerebral demyelination.