Repression of the viral latent promoter BC-R2 in Epstein-Barr virus negative cell lines.
作者信息
Klonjkowski B, Walls D, Gilardi-Hebenstreit P, Perricaudet M
机构信息
Laboratoire de Génétique des Virus Oncogènes, URA 1301 CNRS, Institut Gustave Roussy, Villejuif, France.
出版信息
Biochem Biophys Res Commun. 1992 Dec 30;189(3):1695-700. doi: 10.1016/0006-291x(92)90273-n.
PMID:1336378
Abstract
The regulation of the latent promoter BC-R2 of Epstein-Barr virus (EBV) was examined using the chloramphenicol acetyl transferase (CAT) gene reporter system. A 5' deletion analysis of BC-R2 promoter sequences has been used to characterize a region, described previously as a transcriptional enhancer in EBV positive cell lines, which can repress the BC-R2 transcriptional activity in EBV negative cell lines.
摘要
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