Baykal C, Tulunay G, Bülbül D, Boran N, Köse M F
Department of Gynecologic Oncology, SSK Ankara Women's Hospital, Etlik, Ankara, Turkey.
Gynecol Oncol. 2003 Sep;90(3):667-9. doi: 10.1016/s0090-8258(03)00369-x.
Primary cervical choriocarcinoma seen in a postmenopausal patient is a very rare entity.
Primary choriocarcinoma of the uterine cervix was diagnosed in a 54-year-old woman. She had admitted to our clinic with vaginal bleeding and had been postmenopausal for 1 year at the time of diagnosis. A cervical tumoral mass was seen in her pelvic examination and cervical biopsy revealed squamous cell carcinoma of the cervix. Pelvic examination under anesthesia was done and patient was accepted as FIGO Stage IIA. Type III hysterectomy with bilateral salphingoopherectomy and bilateral pelvic-paraaortic lymph node dissection was carried out. Postoperative pathological evaluation of the surgical specimen showed that case was a primary choriocarcinoma of the cervix.
This is one of the few reported cases of cervical choriocarcinoma in a postmenopausal patient. The most appropriate theory for the development of this tumor is metaplastic differentiation of the tumor from another histologic type.
绝经后患者出现的原发性宫颈绒毛膜癌是一种非常罕见的疾病。
一名54岁女性被诊断为原发性宫颈绒毛膜癌。她因阴道出血入院,诊断时已绝经1年。盆腔检查发现宫颈有肿瘤性肿块,宫颈活检显示为宫颈鳞状细胞癌。在麻醉下进行了盆腔检查,患者被认定为国际妇产科联盟(FIGO)IIA期。实施了III型子宫切除术,同时进行双侧输卵管卵巢切除术和双侧盆腔-腹主动脉旁淋巴结清扫术。手术标本的术后病理评估显示该病例为原发性宫颈绒毛膜癌。
这是少数报道的绝经后患者宫颈绒毛膜癌病例之一。关于该肿瘤发生的最合适理论是肿瘤从另一种组织学类型化生分化而来。