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[一名癫痫患者在发作后出现发育倒退——从CT扫描和SPECT检查结果探讨机制]

[A patient with epilepsy presenting developmental regression after seizures--consideration of the mechanism from the findings of CT-scan and SPECT].

作者信息

Sugama S, Tomita K, Okazaki M, Eto Y, Ito F, Maekawa K

机构信息

Department of Pediatrics, Tokyo Jikei University School of Medicine, Aoto Hospital, Japan.

出版信息

No To Shinkei. 1992 May;44(5):473-6.

PMID:1381601
Abstract

We report a 6-month-old female infant with frequent brief seizures who subsequently showed developmental regression. CT-scans right after her seizures revealed enlargement of bilateral subdural space more on the right side with an evidence to suggest destruction of the blood brain barrier in enhanced CT-scan, CT-scan, one month after the onset, showed diffuse brain atrophy. 123I-SPECT, which was performed 11 days after cessation of her seizures, still showed diffuse hypoperfusion predominantly in the right temporal area, and it returned to normal 3 months after the onset. We discussed the mechanisms of developmental regression in this case from the neuroradiological findings.

摘要

我们报告了一名6个月大的频繁发生短暂惊厥的女婴,其随后出现发育倒退。惊厥发作后立即进行的CT扫描显示双侧硬膜下间隙增宽,右侧更明显,增强CT扫描有证据提示血脑屏障破坏;发病1个月后的CT扫描显示弥漫性脑萎缩。在惊厥停止11天后进行的123I-SPECT仍显示主要在右侧颞叶区域弥漫性灌注不足,发病3个月后恢复正常。我们根据神经放射学检查结果讨论了该病例中发育倒退的机制。

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