II型肺炎球菌的免疫特异性及其向部分特异性的分离。II.
The immunological specificity of type II Pneumococcus and its separation into partial specificities. II.
作者信息
HEIDELBERGER M
出版信息
J Exp Med. 1960 Jan 1;111(1):33-43. doi: 10.1084/jem.111.1.33.
Abstract
Quantitative data are given on the cross reactions in Type II antipneumococcal horse sera of plant gums and hemicelluloses containing multiple terminal groupings of glucuronic acid and/or 4-O-methylglucuronic acid. Great variability is shown both in the reactivities of the polysaccharides and in the antibodies in the sera of different animals immunized with the same antigen. The 4-O-methyl substituent on the glucuronic acid residues in a gum often appears to diminish cross-precipitation with antibodies to S II.
摘要
给出了含有多个葡萄糖醛酸和/或4-O-甲基葡萄糖醛酸末端基团的植物胶和半纤维素在II型抗肺炎球菌马血清中的交叉反应定量数据。在用相同抗原免疫的不同动物血清中，多糖的反应性和抗体均表现出很大的变异性。胶中葡萄糖醛酸残基上的4-O-甲基取代基似乎常常会减少与抗S II抗体的交叉沉淀。
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