Tengborn L, Kjellman B, Elfstrand P O, Bågenholm T
Section of Coagulation Disorders, Sahlgren's Hospital, Göteborg, Sweden.
Acta Paediatr. 1992 Jun-Jul;81(6-7):566-7. doi: 10.1111/j.1651-2227.1992.tb12298.x.
Post-traumatic bleeding from the gingiva in a 16-month-old boy with severe haemophilia A did not stop after treatment with factor VIII concentrate and tranexamic acid, and it was demonstrated that he had developed antibodies to factor VIII. Treatment with recombinant factor VIIa 60-90 micrograms/kg body weight four to eight times daily, together with local measures, stopped the bleeding and no complications were seen.
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